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Antabuse Generic

Antabuse Generic

Disulfiram (dye-SUL-fi-ram)

Availability: In stock

Quantity Strength Unit Price Price Cart
28 Tablets Antabuse 500 mg $1.89 $52.99
84 Tablets Antabuse 500 mg $1.88 $157.99


Disulfiram is recommended for people with drinking problems. It protects the people from drinking alcohol. Drinking of alcohol may lead to physical health issues, mental problems or sometimes social isolation. It is useful in preventing the habit of taking alcohol. It contains the active medicine called Disulfiram. It causes unpleasant effects such as headache, anxiety, nausea, vomiting, blurring of vision and weakness, etc. even after a little amount of alcohol is consumed. These effects persist for 1 hour after taking Anatbuse. So, due to this reason it discourages drinking of alcohol.

Mechanism of action of Antabuse:

Antabuse contains the active medicine called Disulfiram, which inhibits the action of enzyme acetaldehyde dehydrogenase. Hence, it blocks the oxidation of alcohol that is ethanol. This results in accumulation of acetaldehyde in the blood circulation and unpleasant symptoms occur, which is unbearable for the patients.

Under what conditions the use Antabuse is contraindicated?

  • If you have severe heart disease or heart failure problem.
  • If a person has an allergic reaction with Antabuse or its other ingredients.
  • High blood pressure.
  • Severe psychiatric or personality disorder.

What are the drug interactions of Antabuse?

Some drug may show interaction with Antabuse are Rifampicin, Phenytoin, Chlordiazepoxide, Diazepam,  Warfarin, Metronidazole and Isoniazid.

 How to store Antabuse?

It should be stored at room temperature in cool, dry and dark place. Keep it away from children and pets.

What happens in case of overdose?

High dose of this medicine is non toxic. In case of overdose some symptoms appears such as irritability, restlessness, hallucinations and headache. In case of overdose consult your emergency help as soon as possible.

What is the correct administration of Antabuse?

Patients have to stop drinking alcohol at least 12hrs before taking this medicine. Initially start with 500 mg of Antabuse every day for 1 to 2 weeks. After that,125 to 500 mg of Antabuse taken every day as a maintenance dose till patients develop self control. The average maintenance dose should be 250 mg daily. The maintenance therapy may be continued for months or even years.

What are the side effects of Antabuse?

Some common side effects are produced while using this medicine like nausea, flushing, thirst, dizziness, blurred vision, sweating, vomiting, tiredness, polyneuritis, skin rash and confusion.

What are the safety measures a patient has to follow while using Antabuse?

  • Don't consume the medicines and foods that contain alcohol because it may cause Disulfiram-alcohol reactions.
  • It should not be used by pregnant or breastfeeding mothers.
  • It may cause drowsiness, so don't drive after taking this medicine.
  • If you have intolerance to some sugars such as lactose then consult your doctor before taking this medicine.

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