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Sandimmune Injection 100mg/1ml

Sandimmune Injection 100mg/1ml

Generic Cyclosporine

Availability: In stock

Quantity Strength Unit Price Price Cart
50ml $2.88 $143.88


Cyclosporine 100mg is the main active constituent in Sandimmune Injection. It is a cyclic polypeptide immunosuppressant agent comprising of 11 amino acids. Cyclosporine is produced as a metabolite by the fungus species Beauveria nivea. It is used to prevent

Mechanism of Action of Sandimmune Injection

This injection shows its action due to the exact and reversible inhibition of immunocompetent lymphocytes in the G0- or G1-phase of the cycle of the cell, which leads to the inhibition of T-lymphocytes. It also inhibits the production and liberation of lymphocyte including interleukin-2 or T-cell growth factor (TCGF).

Contraindication of Sandimmune Injection 100mg

  • A person allergic to Cyclosporine should avoid use of this injection.
  • A person suffering from liver and kidney disease should not take this injection.

Drug Interaction of Sandimmune Injection 100mg

  • Non- steroidal inflammatory drugs like Ibuprofen, Salicylic acid along with Sandimmune Injection may increase the risk of renal impairment.
  • Anti epileptic drugs like Phenytoin, Carbamazepine along with Sandimmune Injection leads to drug interaction.
  • Antibiotics like Ciprofloxacin, Gentamycin
  • Calcium channel blockers: Cemitidine, Ranitidine
  • Fibric acid derivatives like: Benzafibrate, Methotrexate

Storage Condition of Sandimmune Injection

  • This injection should be stored in cool temperature but not in refrigerator.
  • It should be kept away from direct heat, light and moisture.
  • This injection should be kept away from the reach of children.

Prescribed Dose of Sandimmune Injection

A patient should be given a single dose of 15mg per kg, 4 to 12 hours before the process of transplantation. For renal transplant the lowest initial dose ranges from 10 to 14 mg per kg in a day and this daily dose should be consumed for 1 or 2 weeks and then reduced to 5% every week to maintain a dose of 5 to 10 mg per kg.

Use of Sandimmune Injection may lead to various side effects such as renal dysfunction, tremor, hirsutism, hypertension, and gum hyperplasia, headache, nausea, vomiting, weakness, flushing of face, abdominal pain, allergic reactions like rashes, hives, redness of skin, itching etc.

Precautions To Be Taken While Using Sandimmune Injection 100mg

  • You should induce the prescribed dose of this injection as the increased dose may lead to Hepatotoxicity and Nephrotoxicity.
  • A person suffering from hypertension should use this injection with caution as the use of this injection may lead to hypertension.
  • Avoid taking vaccination therapy along with Sandimmune Injection as this injection reduces the effectiveness of this injection.
  • Pregnant females should take this injection with caution.

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